GPR68 antibody

Catalog No. ABIN265065

Product Details anti-GPR68 Antibody

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR68 antibody is un-conjugated

Application: Western Blotting (WB), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody recognizes OGR1.

Purification: Purified

Immunogen: Recombinant protein derived from human OGR1 (GPR68) protein

Isotype: IgG

Application Details

Application Notes: Western Blot: 5 - 10 μg/mL, Western blot should be visualized using a high sensitivitysecondary/substrate system (i. e. Pierce's SuperSignal West Femto Maximum SensitivitySubstrate).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.08 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for GPR68

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Alternative Name: GPR68 / OGR1 (GPR68 Products)

Synonyms: GPR68 antibody, GPR12A antibody, OGR1 antibody, BB131428 antibody, Ogr1 antibody, G protein-coupled receptor 68 antibody, GPR68 antibody, LOC100348269 antibody, Gpr68 antibody

Background: OGR1 (originally identified as GPR68) is a high-affinity receptor for sphingosylphosphorylcholine (SPC). SPC is a member of a class of bioactive lipids which regulate cellular functions. These functions include cell proliferation and growth inhibition, smooth muscle contration and wound healing. SPC also stimulated signalling pathways that induce tyrosine phosphorylation, activate MAP kinases and protein kinase C, modify ion channel activity and increase intracellular Ca2+ concentration. OGR1 is expressed in placenta, lung, liver, spleen, testis, small intestine and peripheral blood leukocytes. It is not found in thymus, ovary, colon, skeletal muscle, kidney or pancreas.Synonyms: G-protein coupled receptor 68, GPR12A, Ovarian cancer G-protein coupled receptor 1, Sphingosylphosphorylcholine receptor

Gene ID: 8111

NCBI Accession: NP_001171147

UniProt: Q15743