Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SULF2 antibody

SULF2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN265174
  • Target See all SULF2 Antibodies
    SULF2 (Sulfatase 2 (SULF2))
    Reactivity
    • 41
    • 19
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 54
    • 3
    • 1
    Rabbit
    Clonality
    • 55
    • 3
    Polyclonal
    Conjugate
    • 18
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SULF2 antibody is un-conjugated
    Application
    • 45
    • 25
    • 13
    • 13
    • 11
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Specificity
    This antibody detects Sulf2. Antibody tested on human brain lysate.
    Purification
    Purified
    Immunogen
    Synthetic peptide derived from the human Sulf2 protein
    Isotype
    IgG
    Top Product
    Discover our top product SULF2 Primary Antibody
  • Application Notes
    Western blot (0.05-0.1 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline with 0.08 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
  • Target
    SULF2 (Sulfatase 2 (SULF2))
    Alternative Name
    SULF2 (SULF2 Products)
    Synonyms
    Sulf1 antibody, zgc:55612 antibody, SULF2 antibody, si:dkeyp-84g9.1 antibody, wu:fb48e04 antibody, HSULF-2 antibody, xtsulf2 antibody, 2010004N24Rik antibody, AU020235 antibody, MSulf-2 antibody, mKIAA1247 antibody, sulfatase 2a antibody, sulfatase 2 antibody, extracellular sulfatase Sulf-2 antibody, sulfatase 2b antibody, sulfatase 2 S homeolog antibody, sulf2a antibody, SULF2 antibody, LOC100540921 antibody, sulf2 antibody, sulf2b antibody, sulf2.S antibody, Sulf2 antibody
    Background
    Sulf-2 exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Mammalian Sulfs are endoproteolytically processed and secreted into the extracellular space of transfected cells, where they exhibit both arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity against intact heparin. Though the molecular weight of full length human Sulf2 is 100455 Da (870 amino acids), the endogenous Sulf2 is found by western blot to be present at molecular weights of 24.4, 33.7 and 51-60 kDa. Higher molecular weight species may be found depending on tissue and/or cell type. Analysis of human tumor tissue and tumor cell lines suggests that HSulf-1 is misregulated in cancers. HSulf-1 is found in a variety of normal tissues but is down-regulated in tumor cell lines originating from ovarian, breast, pancreatic, renal, and hepatocellular carcinoma. Tumors formed by cells expressing Sulf demonstrate enhanced extracellular matrix deposition. The 6-O-sulfation of heparan sulfate of myeloma tumor cells may be a critical factor in determiningand regulating the in vivo growth of this cancer.Synonyms: Extracellular sulfatase Sulf-2, KIAA1247
    Gene ID
    55959
    NCBI Accession
    NP_001155313
    UniProt
    Q8IWU5
You are here:
Support