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GLI1 antibody (Zinc Finger Protein GLI1)

Details for Product anti-GLI1 Antibody No. ABIN265274, Supplier: Log in to see
Antigen
  • GLI
  • Gli
  • Gli-1
  • gli1.1
  • AV235269
  • Zfp-5
  • Zfp5
Alternatives
anti-Human GLI1 antibody for Western Blotting
Reactivity
Human
129
22
17
5
4
4
2
2
1
1
Host
Rabbit
67
63
4
3
1
Clonality
Polyclonal
Conjugate
This GLI1 antibody is un-conjugated
4
4
4
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
103
24
17
17
12
5
4
3
2
2
1
Supplier
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Immunogen Synthetic peptide derived from human zinc finger protein GLI1
Specificity This antibody detects Zinc Finger Protein GLI1, found in testis, myometrium and fallopian tube.
Purification Affinity chromatography
Alternative Name GLI1 (GLI1 Antibody Abstract)
Background Zinc Finger Protein GLI1 is a member of the Kruppel family of zinc finger proteins. It is thought that it may regulate the transcription of specific genes during normal development and may play a role in craniofacial development and digital development. It also may be involved in the development of the central nervous system and gastrointestinal tract. This protein mediates SHH signaling and thus cell proliferation and differentiation. It has been localized to the cytoplasm and nucleus. It is tethered in the cytoplasm by binding to SUFU and activation and translocalization to the nucleus is promoted by interation with STK36. Protein expression is amplified in glioblastoma cells. Defects in the GLI1 protein may be a cause of breast cancer.Synonyms: GLI, GLI-1, Glioma-associated oncogene, Oncogene GLI, Zinc finger protein GLI1
Gene ID 2735
NCBI Accession NP_001153517
UniProt P08151
Research Area Growth Factors
Pathways Hedgehog Signaling
Application Notes Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer Phosphate buffered saline with 0.08 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
Supplier Images
 image for anti-GLI1 antibody (Zinc Finger Protein GLI1) (ABIN265274) anti-Zinc Finger Protein GLI1 (GLI1) antibody
Background publications Kinzler, Ruppert, Bigner et al.: "The GLI gene is a member of the Kruppel family of zinc finger proteins." in: Nature, Vol. 332, Issue 6162, pp. 371-4, 1988 (PubMed).