Western blot (1: 400 starting dilution). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
Phosphate buffered saline with 0.08 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
Target
SLC16A7
(Solute Carrier Family 16, Member 7 (Monocarboxylic Acid Transporter 2) (SLC16A7))
MCT2 antibody, 4921534N07Rik antibody, Mct2 antibody, zgc:123207 antibody, solute carrier family 16 member 7 antibody, solute carrier family 16 (monocarboxylic acid transporters), member 7 antibody, solute carrier family 16, member 7 (monocarboxylic acid transporter 2) antibody, SLC16A7 antibody, Slc16a7 antibody, slc16a7 antibody
Background
Functions as a proton-linked monocarboxylate transporter and catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a very high affinity pyruvate transporter. MCT2 is a cell membrane, Multi-pass membrane protein with high expression in testis, moderate to low expression in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes. The normal expression of MCT2 is restricted to low levels of expression in normal tissues, but is widely expressed in cancer cells.Synonyms: MCT 2, MCT2, Monocarboxylate transporter 2, Solute carrier family 16 member 7