CLDN10 antibody

Catalog No. ABIN265359

Product Details anti-CLDN10 Antibody

Target: CLDN10 (Claudin 10 (CLDN10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLDN10 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects endogenous levels of Claudin-10 / CLDN10 protein (region surrounding Asn217).

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CLDN10

Target: CLDN10 (Claudin 10 (CLDN10))

Alternative Name: Claudin-10 / CLDN10 (CLDN10 Products)

Synonyms: si:busm1-52i16.3 antibody, si:dz52i16.3 antibody, CLDN10 antibody, DKFZp469F1626 antibody, CPETRL3 antibody, OSP-L antibody, 6720456I16Rik antibody, Cldn10a antibody, Cldn10b antibody, D14Ertd728e antibody, claudin 10a antibody, claudin 10 antibody, cldn10a antibody, CLDN10 antibody, Cldn10 antibody

Background: The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.Synonyms: OSP-Like Protein, OSPL

Molecular Weight: approx. 25 kDa

Gene ID: 9071

NCBI Accession: NP_008915

UniProt: P78369

Pathways: Hepatitis C