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Claudin 7 antibody

CLDN7 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN265365
  • Target See all Claudin 7 (CLDN7) Antibodies
    Claudin 7 (CLDN7)
    Reactivity
    • 62
    • 21
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 59
    • 3
    Rabbit
    Clonality
    • 59
    • 3
    Polyclonal
    Conjugate
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Claudin 7 antibody is un-conjugated
    Application
    • 36
    • 31
    • 25
    • 14
    • 13
    • 13
    • 13
    • 5
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects endogenous levels of Claudin 7 protein. (region surrounding Pro202)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Purity
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product CLDN7 Primary Antibody
  • Application Notes
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Claudin 7 (CLDN7)
    Alternative Name
    Claudin-7 / CLDN7 (CLDN7 Products)
    Synonyms
    cb388 antibody, claudin7 antibody, cldn7 antibody, wu:fd19f08 antibody, MGC53400 antibody, MGC75689 antibody, CLDN7 antibody, CEPTRL2 antibody, CLDN-7 antibody, CPETRL2 antibody, Hs.84359 antibody, claudin-1 antibody, claudin 7b antibody, claudin 7 L homeolog antibody, claudin 7 antibody, cldn7b antibody, cldn7.L antibody, cldn7 antibody, CLDN7 antibody, Cldn7 antibody
    Background
    The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. mRNA studies indicate that claudin-7 is specifically expressed in mouse lung and kidney, but not in heart, brain, spleen, liver, skeletal muscle or testis. The gene encoding human claudin-7 maps to chromosome 17p13.Synonyms: CEPTRL2, CLDN-7, CPETRL2
    Molecular Weight
    approx. 23 kDa
    Gene ID
    1366
    NCBI Accession
    NP_001171951
    UniProt
    O95471
    Pathways
    Hepatitis C
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