JunB antibody

Catalog No. ABIN265490

Product Details anti-JunB Antibody

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JunB antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects endogenous levels of JunB protein. (region surrounding Gly73)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. IHC: 1: 50approx. 1: 200. IP: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for JunB

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Alternative Name: Jun-B (JUNB Products)

Synonyms: AP-1 antibody, junb antibody, wu:cegs2778 antibody, wu:fa92h07 antibody, wu:fq24h03 antibody, zgc:64066 antibody, MGC81322 antibody, JUNB antibody, junbl antibody, wu:fa95h09 antibody, wu:fj44e11 antibody, wu:fj68b07 antibody, zgc:63933 antibody, JunB proto-oncogene, AP-1 transcription factor subunit antibody, JunB proto-oncogene, AP-1 transcription factor subunit a antibody, jun B proto-oncogene L homeolog antibody, jun B proto-oncogene antibody, jun B proto-oncogene S homeolog antibody, JunB proto-oncogene, AP-1 transcription factor subunit b antibody, JUNB antibody, Junb antibody, junba antibody, junb.L antibody, junb antibody, junb.S antibody, junbb antibody

Background: The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein along with c-Fos is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.Synonyms: JUNB, Transcription factor jun-B

Molecular Weight: approx. 38 kDa

Gene ID: 3726

NCBI Accession: NP_002220

UniProt: P17275