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MMP8 antibody

MMP8 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN265533
  • Target See all MMP8 Antibodies
    MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
    Reactivity
    • 61
    • 34
    • 14
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 76
    • 7
    Rabbit
    Clonality
    • 77
    • 6
    Polyclonal
    Conjugate
    • 34
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMP8 antibody is un-conjugated
    Application
    • 69
    • 34
    • 24
    • 11
    • 9
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of MMP-8 protein. (region surrounding Phe445)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific Immunogen.
    Top Product
    Discover our top product MMP8 Primary Antibody
  • Application Notes
    ELISA: 1/5000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
    Alternative Name
    MMP-8 (MMP8 Products)
    Synonyms
    MMP8 antibody, BB138268 antibody, CLG1 antibody, HNC antibody, MMP-8 antibody, PMNL-CL antibody, matrix metallopeptidase 8 antibody, neutrophil collagenase antibody, MMP8 antibody, Mmp8 antibody, LOC100339790 antibody
    Background
    The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-8 (also designated neutrophil collagenase, PMNL collagenase or collagenase-2) degrades fibrillar collagen types I, II and III. Unlike other members of the MMP family, MMP-8 is expressed exclusively in inflammatory conditions. MMP-8 is highly expressed in the postpartum uterus, and it is thought to be involved in the postpartum involution of the uterus. MMP-8 is also the predominant collagenase expressed in ulcers and healing wounds.Synonyms: CLG1, MMP8, Matrix metalloproteinase-8, Neutrophil collagenase, PMNL collagenase, PMNL-CL
    Molecular Weight
    approx. 55 kDa
    Gene ID
    4317
    NCBI Accession
    NP_002415
    UniProt
    P22894
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