CXCR5 antibody (APC)

Catalog No. ABIN2656983

Product Details anti-CXCR5 Antibody (APC)

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CXCR5 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: L138D7

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CXCR5

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Alternative Name: CD185 (CXCR5 Products)

Synonyms: BLR1 antibody, CRL1 antibody, CD185 antibody, MDR15 antibody, Blr1 antibody, CXC-R5 antibody, CXCR-5 antibody, Gpcr6 antibody, NLR antibody, C-X-C motif chemokine receptor 5 antibody, chemokine (C-X-C motif) receptor 5 antibody, CXCR5 antibody, Cxcr5 antibody

Background: CD185 is also known as CXCR5. It is the receptor for chemokine CXCL13/BLC, which is chemotactic for B cells. CXCR5 is expressed on B cells and a subset of T cells in the spleen, neuronal tissue, lymph nodes, and bone marrow. It is important for migration of B cells into the B cell follicles of the spleen and Peyer's patches. Follicular helper T cells (Tfh) also express CXCR5 and the ability of these cells to migrate to the lymph node is modulated by the balanced expression of CCR7 and CXCR5.