CD101 antibody (Alexa Fluor 647)

Catalog No. ABIN2657119

Product Details anti-CD101 Antibody (Alexa Fluor 647)

Target: CD101

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD101 antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Clone: BB27

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CD101

Target: CD101

Alternative Name: CD101 (CD101 Products)

Synonyms: Gm1016 antibody, Gm734 antibody, Igsf2 antibody, EWI-101 antibody, IGSF2 antibody, V7 antibody, CD101 molecule antibody, CD101 antigen antibody, CD101 antibody, Cd101 antibody

Background: CD101 is a type I transmembrane glycoprotein also known as V7 and P126. It is a 120 kD homodimer and member of the EWI family within the Ig superfamily. CD101 is found on monocytes, granulocytes, dendritic cells, and a subpopulation of peripheral blood T cells and activated T cells. It has been reported that CD101 expressing Tregs possess higher inhibitory function. The biological function of CD101 is still not clear, but it has been found that BB27 antibody is able to inhibit T cell proliferative responses and this inhibitory function can be overcome by high doses of IL-2. Activation of CD101 on dendritic cells is able to induce IL-10 production.