LILRB4 antibody (Alexa Fluor 647)
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- Target See all LILRB4 Antibodies
- LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))
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Reactivity
- Mouse
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Host
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Armenian Hamster
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Clonality
- Monoclonal
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Conjugate
- This LILRB4 antibody is conjugated to Alexa Fluor 647
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Application
- Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- Clone
- H1-1
- Isotype
- IgG
- Top Product
- Discover our top product LILRB4 Primary Antibody
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anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) (AA 22-259) antibody
LILRB4 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) (AA 24-206) antibodyLILRB4 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) (AA 22-259) antibodyLILRB4 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) antibodyLILRB4 Reactivity: Human ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) (AA 22-259) antibodyLILRB4 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) (AA 44-73), (N-Term) antibodyLILRB4 Reactivity: Human WB Host: Rabbit Polyclonal RB31065 unconjugated
anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) (AA 1-448) antibodyLILRB4 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C
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- Target
- LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))
- Alternative Name
- CD85k (LILRB4 Products)
- Synonyms
- CD85K antibody, ILT-3 antibody, ILT3 antibody, LIR-5 antibody, LIR5 antibody, Gp49b antibody, HM18 antibody, gp49 antibody, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 antibody, leukocyte immunoglobulin like receptor B4 antibody, leukocyte immunoglobulin-like receptor, subfamily B, member 4A antibody, LILRB4 antibody, Lilrb4a antibody
- Background
- Gp49, also known as ILT3, gp49b1 or CD85k, is a 49 kD glycoprotein expressed on activated NK cells and myeloid cells. It structurally resembles killer inhibitory receptors (KIR). gp49B is a type I membrane protein belonging to the Ig superfamily and contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), while gp49A is a truncated molecule without ITIM. Upon activation following interaction with integrin a vb3, the cytoplasmic tail associates with SHP-1 and SHP-2, which results in downregulation of cell activation and cytokine production.
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