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CD1c antibody (Alexa Fluor 700)

CD1C Reactivity: Human FACS Host: Mouse Monoclonal L161 Alexa Fluor 700
Catalog No. ABIN2657250
  • Target See all CD1c (CD1C) Antibodies
    CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
    Reactivity
    • 47
    • 3
    • 3
    • 1
    • 1
    Human
    Host
    • 26
    • 20
    • 1
    Mouse
    Clonality
    • 28
    • 19
    Monoclonal
    Conjugate
    • 24
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    This CD1c antibody is conjugated to Alexa Fluor 700
    Application
    • 28
    • 27
    • 13
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 700 under optimal conditions.
    Clone
    L161
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD1C Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C
  • Target
    CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
    Alternative Name
    CD1c (CD1C Products)
    Synonyms
    BDCA1 antibody, CD1 antibody, CD1A antibody, R7 antibody, CD1c molecule antibody, CD1C antibody
    Background
    CD1c, also known as R7 or M241, is a 43 kD member of the five CD1 antigens (CD1a-e) in humans. The CD1 Molecules are type I glycoprotein with structural similarities to MHC class I and are non-covalently associated with β2-microglobulin, belonging to the Ig superfamily. CD1c is expressed on cortical thymocytes, Langerhans cells, dendritic cells, and a subset of B cells. It has been reported that CD1c is also expressed on mature T cells in a tightly regulated manner. CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.
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