CCR9 antibody (Alexa Fluor 647)

Catalog No. ABIN2657678

Product Details anti-CCR9 Antibody (Alexa Fluor 647)

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCR9 antibody is conjugated to Alexa Fluor 647

Application: Immunofluorescence (IF)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Clone: CW-1-2

Isotype: IgG2a, IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CCR9

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Alternative Name: CD199 (CCR9 Products)

Synonyms: CC-CKR-9 antibody, CDw199 antibody, GPR-9-6 antibody, GPR28 antibody, A130091K22Rik antibody, Cmkbr10 antibody, C-C motif chemokine receptor 9 antibody, chemokine (C-C motif) receptor 9 antibody, CCR9 antibody, Ccr9 antibody

Background: CCR9 is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in gut-associated immune response. Mouse CCR9 is highly expressed on different stages of thymocytes and upregulated on CD4+CD8+ cells. It is expressed to a much lower level on spleen and lymph node cells. Expression of CCR9 on γ/δ T cells in the intraepithelial and small intestine has been reported. The interaction of CCR9 with its ligand CCL25 (TECK, thymus-expressed chemokine) may direct the trafficking of developing T cells in the thymus and generation of gut-specific immunological memory.