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JAG1 antibody (APC)

JAG1 Reactivity: Mouse CyTOF, ELISA (Capture) Host: Armenian Hamster Monoclonal HMJ1-29 APC
Catalog No. ABIN2658199
  • Target See all JAG1 Antibodies
    JAG1 (Jagged 1 (JAG1))
    Reactivity
    • 79
    • 34
    • 30
    • 1
    Mouse
    Host
    • 68
    • 15
    • 2
    • 1
    Armenian Hamster
    Clonality
    • 65
    • 21
    Monoclonal
    Conjugate
    • 40
    • 9
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This JAG1 antibody is conjugated to APC
    Application
    • 62
    • 32
    • 24
    • 17
    • 11
    • 11
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Cytometry by Time of Flight (CyTOF), ELISA (Capture)
    Purification
    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    Clone
    HMJ1-29
    Isotype
    IgG
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    Discover our top product JAG1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    JAG1 (Jagged 1 (JAG1))
    Alternative Name
    CD339 (JAG1 Products)
    Synonyms
    AGS antibody, AHD antibody, AWS antibody, CD339 antibody, HJ1 antibody, JAGL1 antibody, ABE2 antibody, Gsfabe2 antibody, Htu antibody, Ozz antibody, Ser-1 antibody, JAG1 antibody, jag3 antibody, cb243 antibody, jag1 antibody, sb:cb243 antibody, serrateC antibody, jagged1 antibody, serrate antibody, serrate-1 antibody, x-serrate-1 antibody, jagged 1 antibody, jagged 1b antibody, jagged 1a antibody, jagged 1 L homeolog antibody, JAG1 antibody, Jag1 antibody, jag1 antibody, jag1b antibody, jag1a antibody, jag1.L antibody
    Background
    CD339, also known as Jagged 1, is a 135 kD type 1 transmembrane protein, with one DSL (Delta, Serrate, LagZ) domain, fifteen EGF-like domains, and one cysteine-rich region. Jagged 1 is expressed by many cell types including macrophages, subsets of dendritic cells, astrocytes, stromal, and epithelial cells. CD339 regulates cell fate decisions in various tissues, and has an important role in neurogenesis and development of the cardiovascular system. Studies suggest Jagged 1 is involved in Th2 polarization and Treg induction.
    Pathways
    Notch Signaling, Stem Cell Maintenance
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