Galectin 9 antibody (APC)

Catalog No. ABIN2658314

Product Details anti-Galectin 9 Antibody (APC)

Target: Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Galectin 9 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: RG9-35

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for Galectin 9

Target: Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))

Alternative Name: Galectin-9 (LGALS9 Products)

Synonyms: huat antibody, lgals9a antibody, ecalectin antibody, galectin-9 antibody, Lgals9 antibody, wu:fd20c09 antibody, zgc:111833 antibody, LGALS9 antibody, AA407335 antibody, AI194909 antibody, AI265545 antibody, LGALS35 antibody, Lgals5 antibody, gal-9 antibody, HUAT antibody, LGALS9A antibody, UAT antibody, UATP.I antibody, galectin 9 L homeolog antibody, galectin 9 antibody, lectin, galactoside-binding, soluble, 9 (galectin 9)-like 3 antibody, lectin, galactose binding, soluble 9 antibody, lgals9.L antibody, lgals9 antibody, lgals9l3 antibody, LGALS9 antibody, Lgals9 antibody

Background: Galectin-9 is a mammalian lectin with a molecular weight of 40 kD that has two conserved carbohydrate recognition domains (CRDs) and forms homodimers. It recognizes N-acetyllactosamine (Galbeta1-4GlcNAc) and T-antigen (Galbeta1-3GalNAc). Tim-3 has been reported as its ligand. Galectin-9 is expressed by lymphocytes, dendritic cells, granulocytes, eosinophils, astrocytes, endothelial cells, fibroblasts, and thymus epithelial cells. It may be retained intracellularly or transported to the cell surface whereby cleavage generates a soluble form. Galectin-9 is involved in events such as cell aggregation, adhesion, chemotaxis, and apoptosis, and is important for the regulation of the immune response. Galectin-9 induces regulatory T cells, and suppresses Th1 and Th17 responses.