Keratin 13 (KRT13) antibody

Details for Product No. ABIN265849
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Antigen
Synonyms krt13, CK13, K13, Ka13, Krt-1.13, Krt1-13, ck13, k13
Reactivity
Human
(102), (27), (26), (16), (12), (3), (3), (3), (1), (1), (1)
Host
Mouse
(55), (43), (7), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF)
(81), (48), (26), (25), (23), (22), (13), (10), (8), (4), (1)
Pubmed 1 reference available
Quantity 0.1 mL
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Catalog No. ABIN265849
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Immunogen cultured human epidermoid carcinoma cell line A-431.
Clone KS-1A3
Isotype IgG1
Specificity The reacts with squamous, non-keratinized epithelium, transitional epithelium, pseudostratified epithelium, and myoepithelium.
Cross-Reactivity (Details) Not yet tested in other species.
Purification Ascites
Alternative Name Cytokeratin 13
Background Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediatefilament proteins responsible for the structural integrity of epithelial cells and aresubdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist ofacidic proteins which are arranged in pairs of heterotypic keratin chains. This type Icytokeratin is paired with keratin 4 and expressed in the suprabasal layers ofnon-cornified stratified epithelia. Mutations in this gene and keratin 4 have beenassociated with the autosomal dominant disorder White Sponge Nevus. Alternate Names: anti-CK 13 antibody, anti-CK13 antibody, anti-Cytokeratin13 antibody, anti-K13antibody, anti-Keratin 13 antibody, anti-keratin type I cytoskeletal 13 antibody,anti-Keratin13 antibody, anti-KRT 13 antibody, anti-KRT13 antibody, anti-MGC3781antibody.
Gene Symbol: KRT13
Gene ID 3860
Research Area Signaling, Cytoskeleton, Extracellular Matrix
Application Notes IF: Use at a dilution of 1/100. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
Recommended dilutions: Immunocytochemistry/Immunofluorescence 1:10-1:2000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic Fluid with 0.1 % Sodium Azide, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment -20 °C.
General Macias, Kim, Miliani de Marval et al.: "Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis." in: Cancer research, Vol. 67, Issue 20, pp. 9713-20, 2007 (PubMed).

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