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ESAM antibody (APC)

ESAM Reactivity: Mouse IF, FACS Host: Rat Monoclonal 1G8-ESAM APC
Catalog No. ABIN2658754
  • Target See all ESAM Antibodies
    ESAM (Endothelial Cell Adhesion Molecule (ESAM))
    Reactivity
    • 42
    • 23
    • 16
    Mouse
    Host
    • 56
    • 8
    • 2
    Rat
    Clonality
    • 58
    • 8
    Monoclonal
    Conjugate
    • 27
    • 10
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ESAM antibody is conjugated to APC
    Application
    • 57
    • 31
    • 15
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    Clone
    1G8-ESAM
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product ESAM Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    ESAM (Endothelial Cell Adhesion Molecule (ESAM))
    Alternative Name
    ESAM (ESAM Products)
    Synonyms
    ESAM antibody, sc:d0254 antibody, W117m antibody, 2310008D05Rik antibody, Esam1 antibody, endothelial cell adhesion molecule antibody, endothelial cell adhesion molecule a antibody, endothelial cell-specific adhesion molecule antibody, ESAM antibody, esama antibody, Esam antibody
    Background
    Endothelial cell-selective adhesion molecule (ESAM) is a 55-kD membrane protein composed of two extracellular Ig domains, a single transmembrane domain, and a cytoplasmic domain. ESAM is predominantly expressed at endothelial junctions and on platelets, participating in the migration of neutrophils through the vessel wall by influencing endothelial cell contacts. It impacts vascular permeability and extravasation process. Recently, it was reported that ESAM is a novel marker for murine hematopoietic stem cells (HSCs) in fetal liver. ESAM expression is correlated with HSC activity. The ESAMHi population was highly enriched for multipotent myeloid-erythroid progenitors and primitive progenitors with lymphpoietic activity, and exclusively reconstituted long-term lymphohematopoiesis in lethally irradiated recipients.
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