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TCR V Alpha7.2 antibody (PE-Cy7)

Reactivity: Human FACS Host: Mouse Monoclonal 3C10 PE-Cy7
Catalog No. ABIN2659403
  • Target
    TCR V Alpha7.2
    Reactivity
    Human
    Host
    Mouse
    Clonality
    Monoclonal
    Conjugate
    PE-Cy7
    Application
    Flow Cytometry (FACS)
    Characteristics
    The 3C10 antibody recognizes the Vα7.2 T cell antigen receptor (TCR) α -chain segment which, joined with the Jα33 segment, constitutes an invariant TCR that is characteristics of the mucosal-associated invariant T cells (MAIT cells). MAIT cells are restricted by a nonpolymorphic class Ib major histocompatibility complex (MHC) molecule, MHC-related molecule 1 (MR1). MAIT cells are present in human blood (1-8 % of T cells), mesenteric lymph nodes, liver, and intestinal mucosa. MAIT cells play a role in detecting and fighting off microbial infections.
    Purification
    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
    Clone
    3C10
    Isotype
    IgG1 kappa
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    TCR V Alpha7.2
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