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CD11b antibody (PerCP)

ITGAM Reactivity: Human, Mouse FACS, IP Host: Rat Monoclonal M1-70 PerCP
Catalog No. ABIN2659829
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 258
    • 168
    • 62
    • 33
    • 17
    • 17
    • 16
    • 14
    • 11
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 137
    • 104
    • 103
    • 4
    • 1
    • 1
    Rat
    Clonality
    • 250
    • 96
    • 1
    Monoclonal
    Conjugate
    • 119
    • 37
    • 29
    • 26
    • 20
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
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    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is conjugated to PerCP
    Application
    • 260
    • 83
    • 75
    • 72
    • 59
    • 40
    • 36
    • 27
    • 22
    • 20
    • 13
    • 13
    • 7
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    • 2
    • 2
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    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Cross-Reactivity
    Cynomolgus, Rhesus Monkey, Baboon, Chimpanzee, Rabbit
    Purification
    The antibody was purified by affinity chromatography, and conjugated with PerCP under optimal conditions. The solution is free of unconjugated PerCP and unconjugated antibody.
    Clone
    M1-70
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product ITGAM Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    CD11b (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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