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TICAM1 antibody (Toll-Like Receptor Adaptor Molecule 1) (Internal Region)

Details for Product anti-TICAM1 Antibody No. ABIN266066, Supplier: Log in to see
Antigen
  • AW046014
  • AW547018
  • IIAE6
  • MyD88-3
  • PRVTIRB
  • TICAM-1
  • trif
  • TRIF
Alternatives
anti-Human TICAM1 antibody for Western Blotting
Epitope
Internal Region
29
7
5
4
4
2
2
2
2
2
2
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
70
20
6
2
2
2
1
1
1
Host
Rabbit
73
6
4
Clonality
Polyclonal
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Simple Western (SimWes), Western Blotting (WB)
77
21
17
15
7
5
5
3
2
1
1
1
Supplier
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Immunogen Synthetic peptide made to an internal portion of the mouse TRIF protein (between amino acids 100-180) [UniProt Q80UF7].
Isotype IgG
Specificity The will cross-react with human TRIF, but additional bands may be seen.
Cross-Reactivity (Details) Cross reacts in Mouse. Human reactivity reported in the scientific literature (PMID: 23777661). rat,reactivity reported in scientific literature (PMID: 23447644)
Purification Unpurified
Alternative Name TRIF/TICAM1 (TICAM1 Antibody Abstract)
Background Gene Symbol: TICAM1
Molecular Weight Theoretical MW: 76 kDa
Gene ID 148022, 106759
UniProt Q80UF7
Pathways TLR Signaling
Application Notes Western Blot 1:500-1:1000, Simple Western 1:100, Immunocytochemistry/Immunofluorescence 1:10-1:100
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer Whole sera
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-TICAM1 antibody (Toll-Like Receptor Adaptor Molecule 1) (Internal Region) (ABIN266066) Western blot analysis of TICAM in mouse spleen lysate using ABIN266066 at 1:1000 dilu...
Simple Western (SimWes) image for anti-TICAM1 antibody (Toll-Like Receptor Adaptor Molecule 1) (Internal Region) (ABIN266066) Simple Western: TRIF/TICAM1 Antibody [ABIN2660660] - Simple Western lane view shows a...
Western Blotting (WB) image for anti-TICAM1 antibody (Toll-Like Receptor Adaptor Molecule 1) (Internal Region) (ABIN266066) Western Blot: TRIF/TICAM1 Antibody [ABIN2660660] - Analysis of TRIF in mouse A) intes...
Western Blotting (WB) image for anti-TICAM1 antibody (Toll-Like Receptor Adaptor Molecule 1) (Internal Region) (ABIN266066) Western Blot: TRIF/TICAM1 Antibody [ABIN2660660] - Analysis of TRIF in mouse spleen p...
Immunofluorescence (IF) image for anti-TICAM1 antibody (Toll-Like Receptor Adaptor Molecule 1) (Internal Region) (ABIN266066) Immunocytochemistry/Immunofluorescence: TRIF/TICAM1 Antibody [ABIN2660660] - TRIF ant...
Product cited in: Zhang, Xiang, Wang, Yan, Zhu, Guo, Sengupta, Chen, Loughran, Lu, Wang, Billiar et al.: "Interferon β (IFN-β) Production during the Double-stranded RNA (dsRNA) Response in Hepatocytes Involves Coordinated and Feedforward Signaling through Toll-like Receptor 3 (TLR3), RNA-dependent ..." in: The Journal of biological chemistry, Vol. 291, Issue 29, pp. 15093-107, 2016 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Hu, Cong, Chen, Qi, Wu, Zhou, Yoo, Li, Sun, Wu, Zhao, Chen, Yu, Du, Wang: "Synergy of TLR3 and 7 ligands significantly enhances function of DCs to present inactivated PRRSV antigen through TRIF/MyD88-NF-κB signaling pathway." in: Scientific reports, Vol. 6, pp. 23977, 2016 (PubMed). (Sample species: Pig (Porcine)). Further details: Western Blotting

Ma, Yu, Xie, Sun, Lin, Ding, Luo, Cai: "Toll-Like Receptors Promote Mitochondrial Translocation of Nuclear Transcription Factor Nuclear Factor of Activated T-Cells in Prolonged Microglial Activation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 30, pp. 10799-814, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Immunofluorescence

Haque, Koide, Odkhuu, Tsolmongyn, Naiki, Komatsu, Yoshida, Yokochi: "Mouse pyrin and HIN domain family member 1 (pyhin1) protein positively regulates LPS-induced IFN-β and NO production in macrophages." in: Innate immunity, Vol. 20, Issue 1, pp. 40-8, 2013 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Vogt, Scull, Friling, Horwitz, Donovan, Dorner, Gerold, Labitt, Rice, Ploss: "Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines." in: Virology, Vol. 444, Issue 1-2, pp. 1-11, 2013 (PubMed). Further details: Western Blotting

Abe, Hirasaka, Kagawa, Kohno, Ochi, Utsunomiya, Sakai, Ohno, Teshima-Kondo, Okumura, Oarada, Maekawa, Terao, Mills, Nikawa: "Cbl-b is a critical regulator of macrophage activation associated with obesity-induced insulin resistance in mice." in: Diabetes, Vol. 62, Issue 6, pp. 1957-69, 2013 (PubMed).

Tian, Guo, Liu, Liu, Weng, Dong, Knowlton, Yuan, Lin: "Extracellular HSP60 induces inflammation through activating and up-regulating TLRs in cardiomyocytes." in: Cardiovascular research, Vol. 98, Issue 3, pp. 391-401, 2013 (PubMed). (Sample species: Rat (Rattus)). Further details: Western Blotting

Seleme, Lei, Burg, Goh, Metz, Steele, Tse: "Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice." in: Free radical biology & medicine, Vol. 52, Issue 9, pp. 2047-56, 2012 (PubMed). Further details: Western Blotting

De Luca, Iannitti, Bozza, Beau, Casagrande, DAngelo, Moretti, Cunha, Giovannini, Massi-Benedetti, Carvalho, Boon, Latgé, Romani: "CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease." in: The Journal of clinical investigation, Vol. 122, Issue 5, pp. 1816-31, 2012 (PubMed). Further details: Western Blotting

Zhang, Kim, Bao, Facchinetti, Jung, Ghaffari, Qin, Cheng, Liu: "DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells." in: Immunity, Vol. 34, Issue 6, pp. 866-78, 2011 (PubMed).

Shi, Kehrl: "TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy." in: Science signaling, Vol. 3, Issue 123, pp. ra42, 2010 (PubMed). Further details: Western Blotting

Kong, Thimmulappa, Kombairaju, Biswal: "NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 1, pp. 569-77, 2010 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Wang, Kim, Nakahira, Ryter, Choi: "The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 6, pp. 3809-18, 2009 (PubMed). Further details: Western Blotting,Immunoprecipitation

Dasu, Park, Devaraj, Jialal: "Pioglitazone inhibits Toll-like receptor expression and activity in human monocytes and db/db mice." in: Endocrinology, Vol. 150, Issue 8, pp. 3457-64, 2009 (PubMed). Further details: Western Blotting

Wong, Kwon, Choi, Kim, Nakahira, Hwang: "Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner." in: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27384-92, 2009 (PubMed). Further details: Western Blotting

Shi, Kehrl: "MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33175-82, 2008 (PubMed). Further details: Western Blotting

Krikun, Lockwood, Abrahams, Mor, Paidas, Guller: "Expression of Toll-like receptors in the human decidua." in: Histology and histopathology, Vol. 22, Issue 8, pp. 847-54, 2007 (PubMed). (Sample species: Human). Further details: Western Blotting

Palladino, Johnson, Gupta, Chapman, Ojha: "Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract." in: Biology of reproduction, Vol. 76, Issue 6, pp. 958-64, 2007 (PubMed). (Sample species: Rat (Rattus)). Further details: Western Blotting

Chassin, Goujon, Darche, du Merle, Bens, Cluzeaud, Werts, Ogier-Denis, Le Bouguénec, Buzoni-Gatel, Vandewalle: "Renal collecting duct epithelial cells react to pyelonephritis-associated Escherichia coli by activating distinct TLR4-dependent and -independent inflammatory pathways." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 7, pp. 4773-84, 2006 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Nakahira, Kim, Geng, Nakao, Wang, Murase, Drain, Wang, Sasidhar, Nabel, Takahashi, Lukacs, Ryter, Morita, Choi: "Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts." in: The Journal of experimental medicine, Vol. 203, Issue 10, pp. 2377-89, 2006 (PubMed). Further details: Western Blotting