Toll-Like Receptor Adaptor Molecule 1 (TICAM1) antibody

Details for Product No. ABIN266066
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Antigen
Synonyms IIAE6, MyD88-3, PRVTIRB, TICAM-1, TRIF, AW046014, AW547018
Reactivity
Human
(40), (11), (5), (4)
Host
Rabbit
(46), (3), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(49), (14), (13), (10), (4), (4), (4), (2), (2), (1)
Pubmed 3 references available
Catalog no. ABIN266066
Quantity 0.2 mL
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Immunogen This antibody was developed against a synthetic peptide corresponding to amino acids143-158 of mouse TICAM.
Isotype IgG
Specificity The antibody will cross-react with human TICAM, but additional bands may be seen. Species Reactivity: Cross-reacts with Human, Mouse and Rat. Not yet tested in other species.
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification Serum
Alternative Name TICAM1 / TRIF
Background TICAM (Toll-interleukin 1 receptor domain (TIR)-containing adaptor molecule-1) or TRIF(Toll/IL-1 receptor domain-containing adapter inducing IFN-beta) plays an essential rolein the MyD88-independent signaling of TLR3. Alternate Names: anti-TICAM1 antibody.
Gene ID 148022, 106759
Application Notes Suggested working dilutions: Western Blot 1/500 - 1/1000. Positive Controls: mouse spleen
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.2% gelatin. Preservative: 0.05% Sodium Azide.
Preservative Sodium azide
Storage 4 °C
Supplier Images
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) antibody Western blot analysis of TICAM in mouse spleen lysate using ABIN266066 at 1:1000 dilution.
General Hoebe, Du, Georgel et al.: "Identification of Lps2 as a key transducer of MyD88-independent TIR signalling." in: Nature, Vol. 424, Issue 6950, pp. 743-8, 2003 (PubMed).

Naiki, Michelsen, Zhang et al.: "Transforming growth factor-beta differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling." in: The Journal of biological chemistry, Vol. 280, Issue 7, pp. 5491-5, 2005 (PubMed).

Chassin, Goujon, Darche et al.: "Renal collecting duct epithelial cells react to pyelonephritis-associated Escherichia coli by activating distinct TLR4-dependent and -independent inflammatory pathways." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 7, pp. 4773-84, 2006 (PubMed).

Hosts (46), (3), (1)
Reactivities (40), (11), (5), (4)
Applications (49), (14), (13), (10), (4), (4), (4), (2), (2), (1)
Epitopes (17), (3), (2), (2), (1), (1), (1)
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