NCR1 antibody (Biotin)

Catalog No. ABIN2661053

Product Details anti-NCR1 Antibody (Biotin)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NCR1 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Clone: 9E2

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Alternative Name: CD335 (NCR1 Products)

Synonyms: CD335 antibody, LY94 antibody, NK-p46 antibody, NKP46 antibody, Ly94 antibody, NKp46 antibody, KILR-1 antibody, Nk-p46 antibody, Nkp46 antibody, natural cytotoxicity triggering receptor 1 antibody, NCR1 antibody, Ncr1 antibody

Background: CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is direct-ly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+ NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.

Pathways: Regulation of Leukocyte Mediated Immunity