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- Target See all CD80 Antibodies
- CD80
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD80 antibody is conjugated to Biotin
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Application
- Intracellular Flow Cytometry (ICFC)
- Cross-Reactivity
- Rhesus Monkey
- Purification
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
- Clone
- 2D10
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD80 Primary Antibody
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anti-CD80 (CD80) (AA 35-288) antibody
CD80 Reactivity: Human FACS, WB, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 1G3D7 unconjugated
anti-CD80 (CD80) antibodyCD80 Reactivity: Mouse, Dog FACS, IP, IHC (fro) Host: Armenian Hamster Monoclonal 16-10A1 unconjugated
anti-CD80 (CD80) (AA 38-246) antibodyCD80 Reactivity: Mouse WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibodyCD80 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-233 unconjugated
anti-CD80 (CD80) (AA 251-321) antibodyCD80 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 FITC
anti-CD80 (CD80) antibodyCD80 Reactivity: Human ELISA, IHC, ICC Host: Mouse Monoclonal 2A2 unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (PE)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PE
anti-CD80 (CD80) (Extracellular Domain) antibody (APC)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 APC
anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PerCP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD80
- Alternative Name
- CD80 (CD80 Products)
- Synonyms
- B7 antibody, B7-1 antibody, B7.1 antibody, BB1 antibody, CD28LG antibody, CD28LG1 antibody, LAB7 antibody, B71 antibody, Cd28l antibody, Ly-53 antibody, Ly53 antibody, MIC17 antibody, TSA1 antibody, CD80 molecule antibody, Cd80 molecule antibody, CD80 antigen antibody, CD80 antibody, Cd80 antibody
- Background
- CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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