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Antibody
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anti-Cell Division Cycle 42 GTP Binding Protein 25kDa CDC42
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibody
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| Synonyms |
G25K, CDC42Hs, AI747189, AU018915, CDC42, MGC128612, Cdc42, MGC86687, zgc:55427, zgc:86687, wu:fi33d02, cdc42, g25k, Xcdc42, cdc42hs, MGC79526, LOC100227983 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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Immunofluorescence (IF) (14), Flow Cytometry (FACS) (13), Western Blotting (WB) (9), ELISA (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), ELISA (Detection) (1), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (EM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1)
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| Catalog no. |
ABIN266129 |
| Quantity |
50 µg (1 mg/ml) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CDC42
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Gene ID
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998, 12540, 64465
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Immunogen
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Synthetic peptide, corresponding to amino acids 1-191 of CDC42.
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Description
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This protein is a small GTPase of the Rho subfamily, which regulates signalingpathways that control diverse cellular functions including cell morphology, migration,endocytosis and cell cycle progression. This protein is highly similar to Saccharomycescerevisiae Cdc42, and is able to complement the yeast cdc42 1 mutant. The product ofoncogene Dbl was reported to specifically catalyze the dissociation of GDP from thisprotein. This protein could regulate actin polymerization through its direct binding toNeural Wiskott Aldrich syndrome protein (NWASP), which subsequently activatesArp2/3 complex. Alternative splicing of this gene results in at least two transcriptvariants. Alternate Names: anti-CDC 42 antibody, anti-CDC42Hs antibody, anti-Cell division control protein 42homolog antibody, anti-Cell division cycle 42 antibody, anti-Cell division cycle 42 isoform1 antibody, anti-Cell division cycle 42 isoform 2 antibody, anti-dJ224A6.1.1 antibody,anti-dJ224A6.1.2 antibody, anti-G25K antibody, anti-G25K GTP binding proteinantibody, anti-Growth regulating protein antibody, anti-GTP binding protein 25kDantibody, anti-Small GTP binding protein CDC42 antibody.
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Specificity
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Ab14241 recognises CDC42 isoform 1. Species Reactivity: Cross-reacts with Human, Mouse and Rat.Not yet tested in other species. Localization: Plasma membrane.
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Application Notes
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WB: Use at a dilution of 1/2000. Predicted molecular weight: 24 kDa. Tissue or cellimmunostaining: Use at a starting dilution of 1/200.
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Concentration
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1 mg/ml
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Buffer
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PBS. Preservative: No Preservative.
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Storage
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
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Research Area
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Cancer, Cell Cycle, Kinases/Phosphatases
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Restrictions
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For Research Use only
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Alternatives for antigen "Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42)", type "Antibodies"
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Hosts
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Rabbit (20), Mouse (1)
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Reactivities
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Human (22), Mouse (Murine) (17), Rat (Rattus) (17), Cow (Bovine) (1)
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Applications
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Immunofluorescence (IF) (14), Flow Cytometry (FACS) (13), Western Blotting (WB) (9), ELISA (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), ELISA (Detection) (1), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (EM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1)
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Conjugates
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Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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Center (1)
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Alternatives 
