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IL-33 antibody (Ser109) (Biotin)

IL33 Reactivity: Mouse, Rat FACS Host: Goat Polyclonal Poly5165 Biotin
Catalog No. ABIN2661329
  • Target See all IL-33 (IL33) Antibodies
    IL-33 (IL33) (Interleukin 33 (IL33))
    Binding Specificity
    • 19
    • 16
    • 10
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser109
    Reactivity
    • 81
    • 46
    • 37
    • 9
    • 1
    Mouse, Rat
    Host
    • 102
    • 27
    • 4
    • 3
    • 2
    • 1
    • 1
    Goat
    Clonality
    • 110
    • 30
    Polyclonal
    Conjugate
    • 71
    • 21
    • 13
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-33 antibody is conjugated to Biotin
    Application
    • 84
    • 68
    • 34
    • 26
    • 19
    • 15
    • 14
    • 14
    • 12
    • 10
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Flow Cytometry (FACS)
    Cross-Reactivity
    Rat (Rattus)
    Purification
    The antibody was purified by antigen affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    Immunogen
    Ser109-Isoleucin266 (Accession# NM_133775) was expressed in E. coli.
    Clone
    Poly5165
    Isotype
    Ig Fraction, IgG
    Top Product
    Discover our top product IL33 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 1 % BSA and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IL-33 (IL33) (Interleukin 33 (IL33))
    Alternative Name
    IL-33 (IL33 Products)
    Synonyms
    IL33 antibody, C9orf26 antibody, DVS27 antibody, IL1F11 antibody, NF-HEV antibody, NFEHEV antibody, RP11-575C20.2 antibody, 9230117N10Rik antibody, Il-33 antibody, Il1f11 antibody, RGD1311155 antibody, interleukin 33 antibody, IL33 antibody, Il33 antibody
    Background
    IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33, IL-1b, and IL-18 are synthesized as biologically inactive precursor and are cleaved by the enzyme caspase-1 to be secreted as active mature forms. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signalling events to those observed for IL-1b. In addition, IL-33 is a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties.
    Pathways
    Production of Molecular Mediator of Immune Response
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