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TNFRSF13C antibody (FITC)
TNFRSF13C
Reactivity: Human
WB, FACS, IHC, ICC, Func, ICFC, IF, IP
Host: Mouse
Monoclonal
11C1
FITC
Product Details anti-TNFRSF13C Antibody (FITC)
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Target
See all TNFRSF13C Antibodies
TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Reactivity
All reactivities for TNFRSF13C antibodies
Human
Host
All hosts for TNFRSF13C antibodies
Mouse
Clonality
All clonalities for TNFRSF13C antibodies
Monoclonal
Conjugate
All conjugates for TNFRSF13C antibodies
This TNFRSF13C antibody is conjugated to FITC
Application
All applications for TNFRSF13C antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Functional Studies (Func), Intracellular Flow Cytometry (ICFC), Immunofluorescence (IF), Immunoprecipitation (IP)
Purification
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone
11C1
Isotype
IgG1 kappa
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Discover our top product TNFRSF13C Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for TNFRSF13C
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Target
TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Alternative Name
CD268 (TNFRSF13C Products )
Background
B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-κB activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-κB activation.
Pathways
NF-kappaB Signaling
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