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CD52 antibody (FITC)

CD52 Reactivity: Human FACS, ICFC Host: Mouse Monoclonal HI186 FITC
Catalog No. ABIN2661772
  • Target See all CD52 Antibodies
    CD52
    Reactivity
    • 60
    • 11
    • 7
    • 5
    • 5
    • 1
    Human
    Host
    • 23
    • 20
    • 19
    • 1
    • 1
    Mouse
    Clonality
    • 47
    • 11
    • 3
    Monoclonal
    Conjugate
    • 33
    • 8
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD52 antibody is conjugated to FITC
    Application
    • 49
    • 20
    • 19
    • 16
    • 14
    • 13
    • 12
    • 8
    • 5
    • 5
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Clone
    HI186
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product CD52 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD52
    Alternative Name
    CD52 (CD52 Products)
    Synonyms
    CD52 antibody, AI463198 antibody, B7 antibody, B7-Ag antibody, CAMPATH-1 antibody, CLS1 antibody, MB7 antibody, CDW52 antibody, CE5 antibody, CD52 molecule antibody, CD52 antigen antibody, CD52 antibody, Cd52 antibody
    Background
    CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression. The HI186 antibody is useful for flow cytometry and immunohistochemistry.
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