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CD55 antibody (FITC)

CD55 Reactivity: Human FACS Host: Mouse Monoclonal JS11 FITC
Catalog No. ABIN2661783
  • Target See all CD55 Antibodies
    CD55 (Complement Decay-Accelerating Factor (CD55))
    Reactivity
    • 109
    • 35
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    Human
    Host
    • 68
    • 67
    • 6
    • 6
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 81
    • 69
    • 2
    Monoclonal
    Conjugate
    • 72
    • 17
    • 16
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD55 antibody is conjugated to FITC
    Application
    • 97
    • 77
    • 47
    • 39
    • 32
    • 25
    • 16
    • 15
    • 14
    • 13
    • 9
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Clone
    JS11
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD55 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD55 (Complement Decay-Accelerating Factor (CD55))
    Alternative Name
    CD55 (CD55 Products)
    Synonyms
    CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody
    Background
    CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known as decay-accelerating factor (DAF). It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 accelerates the dissociation of the components of the C3-convertases (namely C2a from C4b in the C4bC2a complex, a C3-convertase of the classical pathway, and factor Bb from the C3bBb complex, a C3-convertase of the alternative pathway) to protect cells from inappropriate damage caused by autologous complement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.
    Pathways
    Complement System, Regulation of Leukocyte Mediated Immunity
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