IL2 antibody (Interleukin 2) (FITC)

Details for Product anti-IL2 Antibody No. ABIN2661943, Supplier: Log in to see
Antigen
  • IL2
  • IL-2
  • il2
  • TCGF
  • lymphokine
  • Il-2
  • POIL2
  • interleukin 2
  • IL2
  • il2
  • Il2
Alternatives
anti-Human IL2 antibody for Blocking Antibody
Reactivity
Human
481
248
98
31
17
10
6
6
5
4
3
3
1
1
Host
Rat
321
275
213
17
5
4
4
Clonality (Clone)
Monoclonal ()
Conjugate
This IL2 antibody is conjugated to FITC
89
51
50
28
21
18
17
14
12
11
9
8
8
7
7
7
7
7
7
7
6
6
6
4
4
4
4
4
4
4
3
3
2
2
2
1
1
Application
Flow Cytometry (FACS)
467
392
226
93
72
49
49
48
41
41
29
26
15
11
10
8
7
7
5
4
3
3
2
2
2
1
1
1
1
1
Options
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Clone MQ1-17H12
Isotype IgG2a kappa
Cross-Reactivity Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Sooty mangabey (Cercocebus atys)
Purification The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Alternative Name IL-2 (IL2 Antibody Abstract)
Background IL-2 is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells, promoting proliferation and maturation. Additionally, IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes.
Research Area Cytokines, Immunology, Virology, Inflammation, Cancer
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.
Supplier Images
Flow Cytometry (FACS) image for anti-IL2 antibody (Interleukin 2)  (FITC) (ABIN2661943) anti-Interleukin 2 (IL2) antibody (FITC)
Flow Cytometry (FACS) image for anti-IL2 antibody (Interleukin 2)  (FITC) (ABIN2661943) anti-Interleukin 2 (IL2) antibody (FITC) (Image 2)
Background publications Dzhagalov, Chambon, He: "Regulation of CD8+ T lymphocyte effector function and macrophage inflammatory cytokine production by retinoic acid receptor gamma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 4, pp. 2113-21, 2007 (PubMed).

Raqib, Ekberg, Sharkar, Bardhan, Zychlinsky, Sansonetti, Andersson: "Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2." in: Infection and immunity, Vol. 70, Issue 6, pp. 3199-207, 2002 (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, 1996 (PubMed).

Andersson, Abrams, Björk, Funa, Litton, Agren, Andersson: "Concomitant in vivo production of 19 different cytokines in human tonsils." in: Immunology, Vol. 83, Issue 1, pp. 16-24, 1995 (PubMed).

Fernandez, Andersson, Andersson, Troye-Blomberg: "Cytokine synthesis analyzed at the single-cell level before and after revaccination with tetanus toxoid." in: European journal of immunology, Vol. 24, Issue 8, pp. 1808-15, 1994 (PubMed).

Skansén-Saphir, Andersson, Björk, Andersson: "Lymphokine production induced by streptococcal pyrogenic exotoxin-A is selectively down-regulated by pooled human IgG." in: European journal of immunology, Vol. 24, Issue 4, pp. 916-22, 1994 (PubMed).

Nisticò: "Communications among central nervous system, neuroendocrine and immune systems: interleukin-2." in: Progress in neurobiology, Vol. 40, Issue 4, pp. 463-75, 1993 (PubMed).

Taniguchi, Minami: "The IL-2/IL-2 receptor system: a current overview." in: Cell, Vol. 73, Issue 1, pp. 5-8, 1993 (PubMed).

Waldmann, Goldman, Top, Grant, Burton, Bamford, Roessler, Horak, Zaknoen, Kasten-Sportes: "The interleukin-2 receptor: a target for immunotherapy." in: Annals of the New York Academy of Sciences, Vol. 685, pp. 603-10, 1993 (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, 1992 (PubMed).