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CD8 antibody (Pacific Blue)

CD8 Reactivity: Human ELISA Host: Mouse Monoclonal SK1 Pacific Blue
Catalog No. ABIN2662308
  • Target See all CD8 Antibodies
    CD8
    Reactivity
    • 227
    • 73
    • 26
    • 17
    • 12
    • 12
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    Human
    Host
    • 231
    • 54
    • 39
    Mouse
    Clonality
    • 268
    • 47
    • 2
    Monoclonal
    Conjugate
    • 97
    • 40
    • 32
    • 24
    • 11
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD8 antibody is conjugated to Pacific Blue
    Application
    • 273
    • 65
    • 64
    • 47
    • 45
    • 42
    • 30
    • 19
    • 17
    • 14
    • 14
    • 14
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus Monkey, Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.
    Clone
    SK1
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD8 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD8
    Alternative Name
    CD8 (CD8 Products)
    Synonyms
    CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, CD8a molecule antibody, CD8A antibody
    Background
    CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
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