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VPREB1 antibody (PE)

VPREB1 Reactivity: Mouse FACS, IF Host: Rat Monoclonal R3 PE
Catalog No. ABIN2662481
  • Target See all VPREB1 Antibodies
    VPREB1 (Pre-B Lymphocyte 1 (VPREB1))
    Reactivity
    • 22
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 25
    • 1
    Rat
    Clonality
    • 25
    • 1
    Monoclonal
    Conjugate
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VPREB1 antibody is conjugated to PE
    Application
    • 18
    • 10
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Purification
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    R3
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product VPREB1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    VPREB1 (Pre-B Lymphocyte 1 (VPREB1))
    Alternative Name
    CD179a (VPREB1 Products)
    Synonyms
    IGI antibody, IGVPB antibody, VPREB antibody, VpreB antibody, CD179a antibody, Vpreb-1 antibody, V-set pre-B cell surrogate light chain 1 antibody, immunoglobulin iota chain antibody, immunoglobulin iota chain-like antibody, pre-B lymphocyte 1 antibody, pre-B lymphocyte gene 1 antibody, VPREB1 antibody, LOC698810 antibody, LOC486411 antibody, Vpreb1 antibody
    Background
    CD179a, also known as VpreB, is an 18 kD member of the Ig superfamily, with an Ig V-like domain structure (that lacks the β strand of a typical V domain). CD179a associates with CD179b to form a surrogate light (SL) chain, which associates with the IgM heavy chain and the CD79a/CD79b heterodimer to form the pre-B cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation, though it has been reported that deficiency of CD179a and/or CD179b impairs the maturation of the B cell precursors beyond the pre-B cell stage.
    Pathways
    Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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