GPR83 antibody (PE)

Catalog No. ABIN2662737

Product Details anti-GPR83 Antibody (PE)

Target: GPR83 (G Protein-Coupled Receptor 83 (GPR83))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GPR83 antibody is conjugated to PE

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: K07JP05

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for GPR83

Target: GPR83 (G Protein-Coupled Receptor 83 (GPR83))

Alternative Name: GPR83 (GPR83 Products)

Synonyms: gpr83 antibody, MGC146295 antibody, GPR83 antibody, GIR antibody, GPR72 antibody, AW045253 antibody, Gir antibody, Gpr72 antibody, RP105 antibody, RP39 antibody, RP82 antibody, G protein-coupled receptor 83 antibody, G protein-coupled receptor 83 S homeolog antibody, GPR83 antibody, gpr83.2.S antibody, gpr83 antibody, Gpr83 antibody

Background: GPR83, also known as GIR, is a seven-pass membrane protein that belongs to the G-protein coupled receptor 1 family. GPR83 is an orphan GPR homologous to tachykinin and neuropeptide Y (NPY) receptors. GPR83 is expressed in the brain and in both murine and human Treg cells. GPR83 is reported to regulate core body temperature and there are four isoforms of GPR83. Studies have suggested that isoform-4, but not isoform-1, is associated with the suppressive functions of Treg cells. The precise role of GPR83 in Treg function is unclear.