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KLRG1 antibody (PE)

KLRG1 Reactivity: Mouse, Human FACS Host: Golden Syrian Hamster Monoclonal 2F1-KLRG1 PE
Catalog No. ABIN2662779
  • Target See all KLRG1 Antibodies
    KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
    Reactivity
    • 27
    • 21
    • 1
    Mouse, Human
    Host
    • 13
    • 11
    • 11
    • 9
    • 1
    Golden Syrian Hamster
    Clonality
    • 29
    • 16
    Monoclonal
    Conjugate
    • 19
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLRG1 antibody is conjugated to PE
    Application
    • 29
    • 13
    • 8
    • 7
    • 2
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    2F1-KLRG1
    Isotype
    IgG
    Top Product
    Discover our top product KLRG1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
    Alternative Name
    KLRG1 (KLRG1 Products)
    Synonyms
    KLRG1 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, 2F1 antibody, CLEC15A antibody, MAFA-2F1 antibody, MAFA-LIKE antibody, killer cell lectin like receptor G1 antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, KLRG1 antibody, Klrg1 antibody
    Background
    Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG1 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.
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