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TCR V Alpha7.2 antibody (PE)

Reactivity: Human FACS Host: Mouse Monoclonal 3C10 PE
Catalog No. ABIN2662859
  • Target
    TCR V Alpha7.2
    Reactivity
    Human
    Host
    Mouse
    Clonality
    Monoclonal
    Conjugate
    PE
    Application
    Flow Cytometry (FACS)
    Characteristics
    The 3C10 antibody recognizes the Vα7.2 T cell antigen receptor (TCR) α -chain segment which, joined with the Jα33 segment, constitutes an invariant TCR that is characteristics of the mucosal-associated invariant T cells (MAIT cells). MAIT cells are restricted by a nonpolymorphic class Ib major histocompatibility complex (MHC) molecule, MHC-related molecule 1 (MR1). MAIT cells are present in human blood (1-8 % of T cells), mesenteric lymph nodes, liver, and intestinal mucosa. MAIT cells play a role in detecting and fighting off microbial infections.
    Purification
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    3C10
    Isotype
    IgG1 kappa
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    TCR V Alpha7.2
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