KIR2DL5A antibody (PE)

Catalog No. ABIN2663070

Product Details anti-KIR2DL5A Antibody (PE)

Target: KIR2DL5A (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KIR2DL5A antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: UP-R1

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for KIR2DL5A

Target: KIR2DL5A (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A))

Alternative Name: CD158f (KIR2DL5A Products)

Synonyms: CD158F antibody, KIR2DL5 antibody, KIR2DL5.1 antibody, KIR2DL5.3 antibody, KIR2DL5B antibody, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A antibody, KIR2DL5A antibody

Background: CD158 Molecules, also known as KIRs (killer cell immunoglobulin-like receptors), are a family of transmembrane proteins with either two (KIR2D) or three (KIR3D) Ig-like extracellular domains. Some KIRs with long cytoplasmic domains contain ITIMs and posses inhibitory functions and others with short cytoplasmic region lack ITIM and have activation functions. 14 polymorphic KIR genes have been reported in humans. CD158f is a 60 kD glycoprotein with 2 Ig-like extracellular domains and long cytoplasmic domains. Its expression is highly polymorphic between individuals and mainly expressed on a subset of NK cells and a small population of T cells. HLA class I alleles are the ligands of CD158f.