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CD276 antibody (PE)

CD276 Reactivity: Mouse FACS Host: Rat Monoclonal RTAA15 PE
Catalog No. ABIN2663287
  • Target See all CD276 Antibodies
    CD276
    Reactivity
    • 60
    • 37
    • 10
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Mouse
    Host
    • 46
    • 16
    • 8
    • 1
    Rat
    Clonality
    • 39
    • 31
    • 1
    Monoclonal
    Conjugate
    • 43
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD276 antibody is conjugated to PE
    Application
    • 52
    • 24
    • 23
    • 14
    • 13
    • 12
    • 9
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    RTAA15
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD276 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD276
    Alternative Name
    CD276 (CD276 Products)
    Synonyms
    sc:d0645 antibody, zgc:158279 antibody, 6030411F23Rik antibody, AU016588 antibody, B7RP-2 antibody, B7h3 antibody, B7H3 antibody, 4Ig-B7-H3 antibody, B7-H3 antibody, CD276 molecule antibody, CD276 molecule S homeolog antibody, CD276 antigen antibody, Cd276 molecule antibody, CD276 antibody, cd276.S antibody, cd276 antibody, Cd276 antibody
    Background
    B7-H3 is a member of the B7 gene family. It has 88 % amino acid sequence identity with human B7-H3. It is mostly expressed on professional APCs, including B cells, macrophages, and dendritic cells. Its expression on dendritic cells appears to be up-regulated by LPS. B7-H3 protein inhibits T cell activation and cytokine production. It was reported that monoclonal antibody against B7-H3 enhanced T cell proliferation in vitro and led to exacerbated EAE in vivo. Therefore, B7-H3 may be a negative regulator on T cell activation and function.
    Pathways
    Cancer Immune Checkpoints
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