IREM1 antibody (PE)

Catalog No. ABIN2663335

Product Details anti-IREM1 Antibody (PE)

Target: IREM1 (Immune Receptor Expressed On Myeloid Cells 1 (IREM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IREM1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: UP-D2

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for IREM1

Target: IREM1 (Immune Receptor Expressed On Myeloid Cells 1 (IREM1))

Alternative Name: CD300F (IREM1 Products)

Synonyms: CLIM1 antibody, CLM-1 antibody, CLM1 antibody, Digr2 antibody, F730004D16Rik antibody, IREM1 antibody, IgSF13 antibody, LMIR3 antibody, Pigr3 antibody, CD300f antibody, RGD1309733 antibody, IREM-1 antibody, NKIR antibody, CD300 molecule like family member F antibody, Cd300 molecule-like family member F antibody, CD300 molecule like family member f antibody, Cd300lf antibody, CD300LF antibody

Background: IREM-1 (immune receptor expressed by myeloid cell 1) is a type I single transmembrane protein encoded by human chromosome 17q24.25. A member of the CD300 (CMRF-35) family and the Ig superfamily, IREM-1 is also known as CD300F, or CD300LF (CD300-like member F). CD300F is expressed on monocytes, granulocytes, and myeloid leukemia cell lines. The cytoplasmic domain of IREM-1 contains an ITIM and associates with the P85α subunit of PI3K (phosphoinositide 3-kinase). IREM-1 also functions as an inhibitory receptor.