SIGLEC7 antibody (PE)

Catalog No. ABIN2663371

Product Details anti-SIGLEC7 Antibody (PE)

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIGLEC7 antibody is conjugated to PE

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: S7-7

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for SIGLEC7

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Alternative Name: CD328 (SIGLEC7 Products)

Synonyms: SIGLEC7 antibody, AIRM1 antibody, CD328 antibody, CDw328 antibody, D-siglec antibody, QA79 antibody, SIGLEC-7 antibody, SIGLEC19P antibody, SIGLECP2 antibody, p75 antibody, p75/AIRM1 antibody, sialic acid-binding Ig-like lectin 7 antibody, sialic acid binding Ig like lectin 7 antibody, LOC468976 antibody, SIGLEC7 antibody

Background: Siglec-7 is a 75 kD type I transmembrane protein and a member of the family of sialic acid-binding immunoglobulin-like lectins (Siglecs), also known as p75/AIRM1. It is primarily found on NK cells and monocytes. The cytoplasmic domain of Siglec-7 contains immunoreceptor tyrosine-based inhibitory motif (ITIM). CD328 mediates sialic acid-dependent cell-cell binding and functions as an inhibitory receptor of NK cells. CD328 preferentially binds to sialylated glycans with α2,8 disialyl and α2,6 sialyl residues.