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CD35 antibody (PE)

CR1 Reactivity: Human FACS Host: Mouse Monoclonal E11 PE
Catalog No. ABIN2663400
  • Target See all CD35 (CR1) Antibodies
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    Reactivity
    • 101
    • 25
    • 22
    • 16
    • 16
    • 15
    • 15
    • 4
    • 3
    Human
    Host
    • 66
    • 37
    • 2
    Mouse
    Clonality
    • 74
    • 28
    • 3
    Monoclonal
    Conjugate
    • 46
    • 11
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD35 antibody is conjugated to PE
    Application
    • 66
    • 37
    • 29
    • 26
    • 21
    • 20
    • 18
    • 16
    • 15
    • 13
    • 13
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    E11
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CR1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    Alternative Name
    CD35 (CR1 Products)
    Synonyms
    C3BR antibody, C4BR antibody, CD35 antibody, KN antibody, C3DR antibody, CD21 antibody, Cr-1 antibody, Cr-2 antibody, Cr1 antibody, CR1-L antibody, CR2 antibody, CR1 antibody, complement C3b/C4b receptor 1 (Knops blood group) antibody, complement receptor 2 antibody, complement component (3d/Epstein Barr virus) receptor 2 antibody, complement receptor type 1 antibody, CR1 antibody, Cr2 antibody, CR2 antibody, LOC718120 antibody
    Background
    CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.
    Pathways
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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