LILRB3 antibody (PE)

Catalog No. ABIN2663606

Product Details anti-LILRB3 Antibody (PE)

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This LILRB3 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: MKT5-1

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for LILRB3

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Alternative Name: CD85a (LILRB3 Products)

Synonyms: CD85A antibody, HL9 antibody, ILT-5 antibody, ILT5 antibody, LILRA6 antibody, LIR-3 antibody, LIR3 antibody, PIRB antibody, Gp91 antibody, Lilrb3 antibody, PIR-B antibody, Pirb antibody, NILR-1 antibody, LILRB3 antibody, leukocyte immunoglobulin like receptor B3 antibody, paired Ig-like receptor B antibody, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 antibody, LILRB3 antibody, Pirb antibody

Background: CD85 is a group of Ig superfamily tansmembrane glycoproteins called Ig-Like Transcripts (ILTs) or Leukocyte Immunoglobulin-like Receptors (LIRs). CD85a is the 110kD member, known as ILT5, LIR-3, or HL9. ILT5 structurally has four extracellular Ig domains and 4 ITIMs in its cytoplasmic tail that provide inhibitory signals. ILT5 is found on the surface of Monocytes/macrophages, granulocytes, NK cells and T-cell subset. ILT5 provides inhibitory signals through interaction with MHC class I molecules.