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ALIX antibody

PDCD6IP Reactivity: Human, Mouse, Frog IF, FACS Host: Mouse Monoclonal 3A9 unconjugated
Catalog No. ABIN2664051
  • Target See all ALIX (PDCD6IP) Antibodies
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    Reactivity
    • 71
    • 32
    • 31
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Frog
    Host
    • 60
    • 11
    • 2
    Mouse
    Clonality
    • 55
    • 17
    Monoclonal
    Conjugate
    • 33
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This ALIX antibody is un-conjugated
    Application
    • 47
    • 26
    • 26
    • 23
    • 12
    • 11
    • 10
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    3A9
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product PDCD6IP Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    Alternative Name
    Alix (PDCD6IP Products)
    Synonyms
    DDBDRAFT_0167145 antibody, DDBDRAFT_0185177 antibody, DDB_0167145 antibody, DDB_0185177 antibody, AIP1 antibody, ALIX antibody, DRIP4 antibody, HP95 antibody, AI480591 antibody, AW544830 antibody, Aip1 antibody, Alix antibody, C76364 antibody, Eig2 antibody, mKIAA1375 antibody, CG12876 antibody, DAIP1 antibody, Dmel\\CG12876 antibody, GB11744 antibody, RGD1561176 antibody, zgc:63638 antibody, wu:fb70d03 antibody, wu:fy65h02 antibody, PDCD6IP antibody, aip1 antibody, alix antibody, hp95 antibody, drip4 antibody, ALG-2 interacting protein X antibody, programmed cell death 6 interacting protein antibody, programmed cell death 6-interacting protein antibody, Programmed cell death 6 interacting protein antibody, programmed cell death 6 interacting protein L homeolog antibody, alxA antibody, PDCD6IP antibody, Pdcd6ip antibody, ALiX antibody, LOC412662 antibody, pdcd6ip antibody, Bm1_48390 antibody, pdcd6ip.L antibody
    Background
    Alix (ALG-2-interacting protein X) is an adaptor protein that was first described for its capacity to bind to the calcium-binding protein ALG-2, the expression of which seemed necessary for cell death. Predicted molecular weight approximately 96 kD. Alix contains an N-terminal Bro1 domain and a C-terminal proline-rich domain (PRD). The PRD contains multiple polyproline motifs, which are potential docking sites for proteins containing SH3 domains, interactwith multiple cellular Alix-binding partners that are involvedin apoptotic induction, endosomal sorting,and endocytosis. Bro1 domain interacts with CHMP4b which is also involved in endosomal sorting.
    Pathways
    p53 Signaling, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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