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CSF2RA antibody
CSF2RA
Reactivity: Human
IF
Host: Mouse
Monoclonal
4H1
unconjugated
Product Details anti-CSF2RA Antibody
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Target
See all CSF2RA Antibodies
CSF2RA
(Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
Reactivity
All reactivities for CSF2RA antibodies
Human
Host
All hosts for CSF2RA antibodies
Mouse
Clonality
All clonalities for CSF2RA antibodies
Monoclonal
Conjugate
All conjugates for CSF2RA antibodies
This CSF2RA antibody is un-conjugated
Application
All applications for CSF2RA antibodies
Immunofluorescence (IF)
Purification
The antibody was purified by affinity chromatography.
Clone
4H1
Isotype
IgG1 kappa
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Discover our top product CSF2RA Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CSF2RA
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Target
CSF2RA
(Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
Alternative Name
CD116 (CSF2RA Products )
Synonyms
CD116 antibody, CDw116 antibody, CSF2R antibody, CSF2RAX antibody, CSF2RAY antibody, CSF2RX antibody, CSF2RY antibody, GM-CSF-R-alpha antibody, GMCSFR antibody, GMR antibody, SMDP4 antibody, Csfgmra antibody, GM-CSF-Ra antibody, GM-CSFR antibody, colony stimulating factor 2 receptor, alpha antibody, colony stimulating factor 2 receptor alpha subunit antibody, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) antibody, CSF2RA antibody, Csf2ra antibody
Background
CD116 is a 70-85 kD α chain of the GM-CSF receptor. It combines with CDw131 β chain to form the high affinity GM-CSF receptor. A soluble form of CD116, which binds GM-CSF with a relatively low affinity, has been identified. In addition, an alternatively spliced form of CD116 with an altered cytoplasmic tail has been described. CD116 is expressed on various myeloid cells including monocytes, macrophages, neutrophils, eosinophils, dendritic cells and their precursors, fibroblasts, and endothelial cells. CD116 is expressed on myeloid leukemias, osteogenic sarcoma cell lines, osteoblast-like cells and breast and lung carcinoma cell lines.
Pathways
JAK-STAT Signaling
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