CD172g antibody, SIRP-B2 antibody, SIRPB2 antibody, SIRPgamma antibody, bA77C3.1 antibody, SIRPG antibody, signal regulatory protein gamma antibody, signal-regulatory protein gamma antibody, SIRPG antibody, LOC716034 antibody, LOC102138723 antibody
Background
Signal Regulatory Proteins (SIRPs) comprise a family of several transmembrane glycoproteins (SIRPα, SIRPβ, and SIRPγ) that belong to immunoglobulin superfamily. SIRPγ is also known as CD172g or SIRPβ2 which is primarily expressed on T cells and a subpopulation of B cells. Like CD172a, the ligand of CD172g is CD47. But the binding affinity with CD172g is lower than CD172a. The biological functions of CD172g include regulation of T-cell transendothelial migration and induction of T cell apoptosis.