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VPREB1 antibody
VPREB1
Reactivity: Human
FACS
Host: Mouse
Monoclonal
HSL96
unconjugated
Product Details anti-VPREB1 Antibody
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Target
See all VPREB1 Antibodies
VPREB1
(Pre-B Lymphocyte 1 (VPREB1))
Reactivity
All reactivities for VPREB1 antibodies
Human
Host
All hosts for VPREB1 antibodies
Mouse
Clonality
All clonalities for VPREB1 antibodies
Monoclonal
Conjugate
All conjugates for VPREB1 antibodies
This VPREB1 antibody is un-conjugated
Application
All applications for VPREB1 antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
HSL96
Isotype
IgG1 kappa
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Discover our top product VPREB1 Primary Antibody
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for VPREB1
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Target
VPREB1
(Pre-B Lymphocyte 1 (VPREB1))
Alternative Name
CD179a (VPREB1 Products )
Synonyms
IGI antibody, IGVPB antibody, VPREB antibody, VpreB antibody, CD179a antibody, Vpreb-1 antibody, V-set pre-B cell surrogate light chain 1 antibody, immunoglobulin iota chain antibody, immunoglobulin iota chain-like antibody, pre-B lymphocyte 1 antibody, pre-B lymphocyte gene 1 antibody, VPREB1 antibody, LOC698810 antibody, LOC486411 antibody, Vpreb1 antibody
Background
CD179a is an 18 kD Ig V-like protein expressed on pro-B and early pre-B cells. It is a member of the Ig gene superfamily, known as VpreB, VPREB1, and IGVPB. CD179a noncovalently associates with CD179b (λ5) to form a surrogate light (SL) chain. The SL chain is complexed with membrane bound IgM heavy (μH) chain and CD79a/CD79b heterodimer to form the pre-B-cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation though it has been reported that the pre-BCR complex plays a critical role in B cell development.
Pathways
Production of Molecular Mediator of Immune Response , Regulation of Cell Size
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