CD200 Receptor 3 (CD200R3) antibody

Details for Product No. ABIN2664372, Supplier: Log in to see
Antigen
  • 4733401I18Rik
  • 4833409J19Rik
  • AI505817
  • BB106877
  • mCD200RLb
  • CD200 receptor 3
  • Cd200r3
Reactivity
Mouse (Murine)
17
Host
Rat
11
4
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
7
4
1
Application
Intracellular Flow Cytometry (ICFC)
15
2
2
2
2
1
Options
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Clone Ba160
Isotype IgG2b kappa
Purification The antibody was purified by affinity chromatography.
Alternative Name CD200R3 (CD200R3 Antibody Abstract)
Background CD200R3, also known as CD200RLb and OX-2 Receptor 3, is a disulfide-linked dimmeric CD200R-like receptor which belongs to immunoglobulin superfamily. Its positively charged aminio acid lysinein associates with ITAM- or YxxM motif-bearing adaptor molecules such as DAP12, DAP10, FcRγ, and CD3ζ. CD200R3 functions as an activating receptor to regulate IgE independent immune response.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.
Supplier Images
Flow Cytometry (FACS) image for anti-CD200 Receptor 3 (CD200R3) antibody (ABIN2664372) anti-CD200 Receptor 3 (CD200R3) antibody
Flow Cytometry (FACS) image for anti-CD200 Receptor 3 (CD200R3) antibody (ABIN2664372) anti-CD200 Receptor 3 (CD200R3) antibody (Image 2)
Background publications Sato, Eizumi, Fukaya, Fujita, Sato, Takagi, Yamamoto, Yamashita, Hijikata, Kitamura, Ohara, Yamasaki, Saito, Sato: "Naturally occurring regulatory dendritic cells regulate murine cutaneous chronic graft-versus-host disease." in: Blood, Vol. 113, Issue 19, pp. 4780-9, 2009 (PubMed).

Kojima, Obata, Mukai, Sato, Takai, Minegishi, Karasuyama: "Mast cells and basophils are selectively activated in vitro and in vivo through CD200R3 in an IgE-independent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 10, pp. 7093-100, 2007 (PubMed).

Voehringer, Rosen, Lanier, Locksley: "CD200 receptor family members represent novel DAP12-associated activating receptors on basophils and mast cells." in: The Journal of biological chemistry, Vol. 279, Issue 52, pp. 54117-23, 2004 (PubMed).