IL18R1 antibody

Catalog No. ABIN2664402

Product Details anti-IL18R1 Antibody

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL18R1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Purification: The antibody was purified by affinity chromatography.

Clone: H44

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for IL18R1

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Alternative Name: CD218a (IL18R1 Products)

Synonyms: CD218a antibody, CDw218a antibody, IL-1Rrp antibody, IL18RA antibody, IL1RRP antibody, IL-1R9 antibody, IL1R9 antibody, IL1RAPL-2 antibody, TIGIRR-1 antibody, Il18ralpha antibody, Il1rrp antibody, IL-18Ra antibody, IL18R1 antibody, interleukin 18 receptor 1 antibody, interleukin 1 receptor accessory protein like 2 antibody, IL18R1 antibody, IL1RAPL2 antibody, Il18r1 antibody

Background: IL-18 receptor is composed of an α and a β subunit that combine to form a high affinity receptor for IL-18. IL-18 receptor α chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis.