CD300LG antibody

Catalog No. ABIN2664534

Product Details anti-CD300LG Antibody

Target: CD300LG (TREM4) (Triggering Receptor Expressed On Myeloid Cells 4 (TREM4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD300LG antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: The antibody was purified by affinity chromatography.

Clone: ZAQ5

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD300LG

Target: CD300LG (TREM4) (Triggering Receptor Expressed On Myeloid Cells 4 (TREM4))

Alternative Name: CD300LG (TREM4 Products)

Synonyms: RGD1311074 antibody, 2310016B05Rik antibody, Clm9 antibody, D11Ertd736e antibody, CLM-9 antibody, CLM9 antibody, NEPMUCIN antibody, TREM-4 antibody, TREM4 antibody, Cd300 molecule-like family member G antibody, CD300 molecule like family member G antibody, CD300 molecule like family member g antibody, triggering receptor expressed on myeloid cells 4 antibody, Cd300lg antibody, CD300LG antibody, Trem4 antibody

Background: CD300LG, also known as nepmucin (a not expressed in Peyer's patches mucin), is a member of the CD300 antigen like family. It is a 50-95 kD glycoprotein with one IgV like domain and one mucin like domain and four isoforms are produced by alternative splicing. Nepmucin is expressed on high endothelial venules (HEV) from lymph nodes, but is absent on HEV from the Peyer's patches. CD300LG mediates lymphocyte adhesion through the intraction of its Ig domain with ICAM-1 and rolling on HEVs through the interaction of its mucin like domain with L-selectine. Also, it may play a role in the molecular transcytosis across the capillary endothelium.