TNFSF18 antibody
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- Target See all TNFSF18 Antibodies
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This TNFSF18 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- 5F1
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product TNFSF18 Primary Antibody
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 101-199) antibody
TNFSF18 Reactivity: Human, Mouse WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 1-177) antibodyTNFSF18 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 70-199) antibodyTNFSF18 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 72-199) antibodyTNFSF18 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 68-177) antibodyTNFSF18 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 6F7 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) antibodyTNFSF18 Reactivity: Human WB, IHC (p), ELISA (Capture) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) antibodyTNFSF18 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) antibodyTNFSF18 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) antibodyTNFSF18 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 68-177) antibodyTNFSF18 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
- Alternative Name
- GITR Ligand (TNFSF18 Products)
- Synonyms
- Gitrl antibody, AITRL antibody, GITRL antibody, TL6 antibody, hGITRL antibody, TNLG2A antibody, tumor necrosis factor (ligand) superfamily, member 18 antibody, TNF superfamily member 18 antibody, Tnfsf18 antibody, TNFSF18 antibody
- Background
- GITR ligand (GITRL) is a member of the TNF superfamily, also known as TNFSF18 or TL6. It is expressed on B cells, macrophages, dendritic cells, and endothelial cells. The expression of GITRL on the dendritic cell surface can be transiently upregulated, and then rapidly downregulated, by LPS stimulation. GITRL binds to its receptor, GITR, to costimulate T cell activation, proliferation, and cytokine production, inhibit the suppressive functions of CD4+CD25+ Tregs, and induce macrophage activation. GITR-GITRL interaction has been implicated as an essential regulator of the immune response to self antigens and phathogens.
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