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IL-4 antibody

IL4 Reactivity: Human BCA Host: Mouse Monoclonal 8D4-8 unconjugated
Catalog No. ABIN2665172
  • Target See all IL-4 (IL4) Antibodies
    IL-4 (IL4) (Interleukin 4 (IL4))
    Reactivity
    • 135
    • 57
    • 22
    • 14
    • 11
    • 10
    • 10
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 109
    • 59
    • 56
    • 7
    • 3
    • 2
    Mouse
    Clonality
    • 126
    • 107
    • 1
    Monoclonal
    Conjugate
    • 138
    • 33
    • 16
    • 13
    • 10
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-4 antibody is un-conjugated
    Application
    • 118
    • 110
    • 70
    • 61
    • 25
    • 20
    • 19
    • 16
    • 13
    • 13
    • 12
    • 11
    • 9
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Biochemical Assay (BCA)
    Cross-Reactivity
    Chimpanzee, Cynomolgus, Rhesus Monkey, Baboon
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    8D4-8
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product IL4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IL-4 (IL4) (Interleukin 4 (IL4))
    Alternative Name
    IL-4 (IL4 Products)
    Synonyms
    IL4 antibody, IL-4 antibody, BCGF-1 antibody, BCGF1 antibody, BSF-1 antibody, BSF1 antibody, Il-4 antibody, Il4e12 antibody, IL2 antibody, interleukin 4 antibody, IL4 antibody, Il4 antibody
    Background
    IL-4 is a pleiotropic cytokine that is produced by activated T cells mast cells and basophils. IL-4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10 and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells. The 8D4-8 antibody can neutralize the bioactivity of natural or recombinant IL-4.
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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