Galectin 3 antibody (AA 151-251)

Catalog No. ABIN2665255

Product Details anti-Galectin 3 Antibody

Target: Galectin 3 (LGALS3)

Binding Specificity: AA 151-251

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Galectin 3 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purification: The antibody was purified by affinity chromatography.

Clone: Gal397

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: Mac-2 (LGALS3 Products)

Synonyms: CBP 35 antibody, Gal-3 antibody, Galectin-3 antibody, leg3 antibody, galactoside-binding antibody, galectin-3 antibody, lectin antibody, soluble antibody, CBP35 antibody, GAL3 antibody, GALBP antibody, GALIG antibody, L31 antibody, LGALS2 antibody, MAC2 antibody, MGC52947 antibody, MGC75803 antibody, LGALS3 antibody, gal-3 antibody, GBP antibody, L-34 antibody, Mac-2 antibody, gal3 antibody, galectin 3 antibody, Galectin-3 antibody, avian beta-defensin 3 antibody, lectin, galactoside-binding, soluble, 3 L homeolog antibody, lectin, galactoside-binding, soluble, 3 antibody, galectin 2 antibody, lectin, galactose binding, soluble 3 antibody, LGALS3 antibody, leg3 antibody, AvBD3 antibody, lgals3.L antibody, lgals3 antibody, LGALS2 antibody, Lgals3 antibody

Target Type: Chemical

Background: Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and εBP. It is a member of animal β-galactoside-binding protein family that is expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to β-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motif that is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule.

Pathways: RTK Signaling